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37,38 Other than lipid accumulation in kidney tissues, CKD patients always have dyslipidemia, which is characterized by high levels of serum triglycerides, LDL-cholesterol (LDL-C), and low HDL-cholesterol (HDL-C) levels

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(3) The observed decrease in carnitine and CPT I expression in cardiac tissues by SUN was parallel to the increase in cardiac index, cardiac enzymes and myocardial fibrosis which may point to the possible contribution of carnitine deficiency and the inhibition of CPT I as possible mechanisms in SUN-induced cardiotoxicity

The effects of L-Carnitine supplementation in muscle cramp patients were studied in the Clinical Neuropharmacology journal (Bachman et al., 1996)