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Research has demonstrated a negative correlation between leukocyte concentration in semen and sperm concentration and vitality, indicating that inflammation of the male reproductive system significantly impairs reproductive function [1]

Despite the promising advances of these models, appropriate toxicity end-points and sensitive translational biomarkers are yet to be identified

In addition, the hypermethylated status of genes such as HPS4 , LZTFL1 , FARS2 , SGMS2 , ABHD2 , and RNF144A can serve as biomarkers for clinical staging of ovarian cancer [19]

Probiotics reduce vaginal atrophy through Lactobacillus strains that maintain vaginal pH and reduce infection risk despite lower estrogen levels