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Clinically, GABA and GABA analogs have been investigated as potential analgesics in CIPN and other conditions (Zarba et al., 2020) because GABAergic neurons and receptors are involved in coordination of the perception and response to noxious stimuli (Mullins et al., 2014) might help direct the development and optimization of non-invasive interventions to maximize GABAergic signaling through endogenous mechanisms

Magnesium, commonly depleted by certain chemotherapy drugs, plays crucial roles in energy production, muscle function, and nerve transmission

10.1038/ncomms9425 8 BarrangouR.van PijkerenJ.-P

Positioning and stretching are also useful and necessary for decreasing spasticity and maintaining ROM at the affected joints and may even decrease long-term spasticity (6,65)

Gut microbiota mediates the protective effects of dietary capsaicin against chronic low-grade inflammation and associated obesity induced by high-fat diet