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Changes in the sensory and barrier functions of the cells lining the bladder (Figure 2) are thought to play a role

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The DRI modification that stabilizes the peptide against degradation also means its elimination kinetics in humans are unknown

Autonomic dysreflexia is a medical emergency and may require urgent attention

Riboflavin deficiency Vitamin B2 deficiency is relatively uncommon in developed countries, being most frequent in poorer areas of Asia and Africa (Mahabadi et al, 2023)