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Oncotarget 7 , 19731983 (2016)

How we evaluated berberine supplements We considered three major criteria when comparing berberine supplements: Safety: Since the FDA doesnt regulate supplements the same way as food and prescription medications, we consider product safety and transparent testing to be the highest priority

[] Despite the clinical benefits of newer bile acid sequestrants, such as colesevelam on glucose metabolism, they are not effective enough to treat patients with cholestatic pruritus

Yamazaki, T., Kawai, C., Yamauchi, A

The compelling hypothesis, and the one driving current research, is based on an indirect mechanism of action