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Specific contributions include: Modulating Innate Responses: GPx1 influences endothelial CD14 levels, essential for Toll-like receptor signaling in bacterial detection

Lohmann and Karst, 2007) ( Figure 1 )

10.1007/s12275-016-6137-1 J

Lipid peroxidation is a process under which oxidants such as free radicals or nonradical species attack lipids containing carboncarbon double bond(s), especially polyunsaturated fatty acids (PUFAs) that involve hydrogen abstraction from a carbon, with oxygen insertion resulting in lipid peroxyl radicals and hydroperoxides

As an antioxidant, glutathione helps protect cells from damage