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A 5,000 mcg dose is typically used in specific cases like: Severe deficiency Pernicious anemia Absorption problems Certain neurological symptoms Doctor-supervised treatment plans For an average healthy person, that amount is often unnecessary

It could help men with things like getting an erection, and may also enhance women's sexual function, but it is not FDA-approved for this use

The pathology of -syn aggregation and dopaminergic neuron loss in the peripheral skin resembles that in the central nervous system, indicating a strong correlation between cutaneous and CNS pathology [98]

Direct NAD+ supplementation has considerably more human research behind it

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