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The aged mouse study involved small sample sizes

3.2 BBB disruption by traumatic brain injury Traumatic brain injury (TBI) is associated with epilepsy

DS patients contain approximately 50% higher SOD1 levels in various DS cells and tissues, including erythrocytes, brain, fibroblasts, B and T lymphocytes, which leads to chronic OS and manifests as a wide array of neurological symptoms (Turrens, 2001