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Targeting the Melanocortin System to Treat Hereditary Obesity Table 3: Selected genetic causes of obesity Setmelanotide, an MC4R agonist and first-in-class treatment for hereditary obesity Drug Development Pipeline for Genetic Causes of Obesity 6

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A comparison of the ROS handling abilities in the cell lines with gill cells from live fish would reduce uncertainties related to the relevance of the models for in vivo effects of cellular processes involving ROS-formation and handling processes