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The protein pellet was washed with 0.5 ml cold methanol ( 80 C) and centrifuged (21,000 g , 10 min, 4 C) twice

Nrf2 is a transcription factor that can bind to promoter regions of genes that are essential for antioxidative, cell survival, and cell proliferation signaling, such as BDNF, CAT, SOD1 and TrxR ( in vivo following the administration of erinacine-free H