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10.14336/AD.2020.0105 56 LiZ.JiangT.LuQ.XuK.HeJ.XieL.et al (2020a)

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3 Molecular mechanisms of diabetic nephropathy 3.1 Inflammation and immune regulation imbalance The progression of DN is closely associated with dysregulated inflammation and immune responses (Figure 2), where the TGF-/Smad3 signaling pathway serves as a central driver of renal fibrosis