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Potentials for practical applications of equine antimicrobial peptides in horses can be deduced from results obtained with antimicrobial peptides in general

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This perspective is reinforced by the central gain model of tinnitus, which suggests that tinnitus results from an abnormal compensatory increase in gain (i.e., neural amplification) within the CAS to compensate for a loss of sensory input from the cochlea 9,10,11

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In the mouse model of bleomycin-induced lung fibrosis, Gpx3 levels in tissue and BALF were increased in the inflammatory (day 37) and fibrotic (day 1428) phase 35,46 , but had returned to baseline after resolution of fibrosis at day 56