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The surface expression of wtGHSR and various mutants in HEK-293T cells was determined and confirmed using FACS with a fluorescent FLAG M1 antibody (homemade)

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GH and IGF-1 are involved in regulating adipocyte differentiation and proliferation and furthermore, sex hormones influence adipose tissue in numerous different ways such as gene expression and function ( A recently published study reported that periodic fasting or a fasting-mimicking diet can enhance the anti-cancer activity of anti-estrogen therapies by lowering the circulating levels IGF-1, insulin and leptin and consequently inhibiting the AKT mTOR pathway (Tsujimoto et al., 2017)

Ipamorelins pentapeptide structure features non-natural amino acids including aminoisobutyric acid (Aib) and D-2-naphthylalanine (D-2-Nal), contributing to its selective ghrelin receptor binding properties

Does "not FDA-approved" mean a peptide is illegal or unsafe