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The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA

Du, S., Hu, X., Menndez-Arias, L., Zhan, P

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Additionally, histone methyltransferase G9a inhibitors have been recently shown to regulate intestinal inflammation by enhancing cholesterol metabolism in CD4 + T cells, leading to the development of Tregs in vivo and in vitro [55]