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Notably, pre-treatment with NAC inhibited dopamine-induced cell death, restored GSH levels, decreased HO-1 expression, and suppressed the activation of caspase-3 and caspase-9

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Bcl-2 proteins possess a BH-3 domain where GSH binds and since its presence seems to be correlated to the increase of the GSH pool in the nucleus, it is possible that Bcl-2 proteins are involved in GSH translocation into the nucleus through Bcl-2 associated athanogene pores (BAG) [39,40,41]

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Cardiac valvulopathy associated with exposure to fenfluramine or dexfenfluramine: U.S

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