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Because your body can store B12 for 2 to 5 years, a serious B12 deficiency is rare

GRAS (Generally Recognized as Safe) is a food safety designation that applies to dietary supplements and food additivesit establishes safety at intended doses but NOT efficacy for any therapeutic claim

The choice typically comes down to your provider's preference, your absorption profile, and what your pharmacy stocks

If levels are very low, initial weekly visits can help build a foundation, then you may shift to every two to four weeks for maintenance

Microscopy experiments on a 3D spheroid model of MYCN-driven NB support this hypothesis