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In the retrospective MFU-V and diluted CaHA study, subjects received treatment with MFUS at a depth of 4.5 mm at 4MHz, followed by the 7 Mhz, 3 mm depth transducer

This underscores the necessity of investigating astrocytes beyond bulk tissue analyses, as single-cell studies reveal that astrocyte subpopulations exhibit heterogeneous responses to pathological stimuli

The study authors also indicated that PRP injections were associated with better pain reduction results compared to extracorporeal shockwave therapy

Since computer simulations are highly dependent on previous experimental data, and the pathways and mechanisms of NPs toxic effects have not been fully elucidated, computer models may not be able to predict the toxic effects of NPs accurately

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