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Description

Huang et al, 1999

Additionally, the NNMT substrate nicotinamide 12 is metabolized by the microbiome 56,57 , and thus NNMTi may modulate substrate availability, potentially influencing microbial metabolic capacity to drive the NNMTi-mediated weight loss

In a large series, 26% of patients presented with dystonia, and among them, 80% presented with craniocervical dystonia, including blepharospasm, cervical dystonia, lingual dystonia, and jaw-opening dystonia [ 41 ]