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75 The poor water solubility and poor absorption of curcumin, however, prevent its widespread use as an anticancer treatment and the bioavailability of curcumin remains incredibly low

doi:10.1016/0149-7634(84)90022-8 PMID: 6371193 5

Furthermore, because a metabolic profile is summative of all the biochemical processes occurring in the body at a given time, it makes no presumption about the relative importance of these processes and so is more likely than a candidate approach to be able to highlight differences between disease groups and to identify changes occurring during therapy

For instance, a 2023 study evaluated the relationship between hydration and cognitive function in older adults