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Proteomic and metabolite profiling reveals profound structural and metabolic reorganization of adipocyte mitochondria in obesity

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While this allowed us to examine the impact of circulating factors associated with an obese intrauterine environment, it limited our ability to examine how other maternal factors, such as maternal gestational diabetes mellitus (GDM), interact with maternal obesity to influence offspring risk for MASLD and limits the generalizability of our findings to other patient groups

To date, no large controlled in vivo studies evaluating the TB-500 and BPC-157 combination have been published in peer-reviewed literature