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Of note, many cell types can be the source of GM-CSF during CNS autoimmunity, such as CD8 + T cells, innate lymphoid cells (ILCs), NK cells, T cells, but CD4 + T lymphocytes were described as the main producers of this cytokine (20)

Taken together, the reduction in biofilms increased antigen release and allowed better access to antigens by immune cells

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CPT1A P479L mutation attenuates normalized gene expression and protein concentrations of PD biomarkers in the midbrain Other hallmarks of PD are the downregulation of tyrosine hydroxylase (TH) in the striatum and the general deposition of -syn in the brain 1,31