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Nat Genet 2024;56:2392-406

169 Therefore, impaired synthesis of both QUIN and serotonin in autism may be related through dysregulated KP metabolism, which is likely due to abnormal mRNA and protein expression of KP enzymes, leading to altered cell signaling during early development

Interestingly, although HA.28-GLUT1 cells showed increased surface expression of CCR4 and CCR6, they secreted increased levels of Th 1 and Th 2 -associated cytokines and IL-22 compared to control cells following antigen challenge (Fig

| May 25, 2022 Brad went over the results in details and was able to answer all my questions about the results

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