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Farhood B, Aliasgharzadeh A, Amini P, Rezaeyan A, Tavassoli A, Motevaseli E, et al

Blood (2019) 134:4458

163 (5), e361e373

Overactivation, use during late-stage disease characterized by NAD + depletion, or lack of tissue specificity may result in adverse effects, including oxidative damage, energy imbalance, or cell death