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Treatment of oxaliplatin-induced peripheral neuropathy by intravenous mangafodipir

10.1021/pr800422e 159 SiemsenD

Remarkably, in vitro experiments using soluble SNAREs indicate that the binding of the M105I mutant protein to cis-SNARE complexes and the NSF-mediated dissociation of these complexes were comparable to those observed with -SNAP WT 14 , suggesting that the hyh phenotype results from the -SNAP hypomorphism and not from an altered protein function per se

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