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Systematic meta-analyses have demonstrated that depression patients have significantly elevated serum IL-6, TNF-, and C-reactive protein (CRP) levels (Osimo et al., 2020)

alterations in mood, including depression and anxiety

I've since bought up-to-date ampoules and, having various symptoms which may be related to low levels, I've decided to do alt days for a couple of weeks, then back to 2-3 monthly

From the Coach: Grit

Meanwhile, correlation analysis between MANF level and clinical variables in ICC showed that high expression of MANF was associated with larger tumor diameter ( P = 0.026), TNM stage ( P = 0.000), and distant metastasis ( P = 0.017) (Supplementary Table 1)