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Memorial Sloan-Kettering Cancer Center

The cause is not completely understood but involves a T cell-mediated immune response triggered by a variety of factors which may include nutritional deficiencies, local trauma, stress, hormonal influences, allergies, genetic predisposition, certain foods, dehydration, some food additives, or some hygienic chemical additives like SDS (common in toothpaste)

Xiang L, Fang C, Feng J, Tan Y, Wu Q, Zhou X, Li J, Gong T

Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies

In addition to their contribution to the formation of the NP, notochordal cells also aid in the synthesis of ECM during the formation of the spinal column through the stimulation of growth factors (Pattappa et al., 2012)