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Several studies have shown that injections dissolved in saline are less painful than those dissolved in water because the bodys natural salinity more closely matches that of saline, eliminating the need to equalize salinity levels

For instance, emulsions and micelles can encapsulate carotenoids, improving their solubility in water-based solutions 48

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Yang S, Zheng Y, Hou X (2019) Lipoxin A4 restores oxidative stress-induced vascular endothelial cell injury and thrombosis-related factor expression by its receptor-mediated activation of Nrf2-HO-1 axis

Synthesis and biological evaluation of EC20: a new folate-derived, 99mTc-based radiopharmaceutical