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Disease pathogenesis is predominantly driven by the synergistic action of core pathological mechanisms, including -syn aggregation, oxidative stress (OS), mitochondrial dysfunction, and neuroinflammation

Future research should prioritize well-designed clinical trials to comprehensively assess the efficacy and safety of TCM interventions for PD

The analysis followed the intention-to-treat principle, utilizing linear regression to impute missing data from participants who dropped out during the study

(2011), who reported that intermittent energy restriction led to improvements in oxidative stress markers in overweight women 8

Renton AE, Chio A, Traynor BJ