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The combination of metformin and Ginkgo biloba extract did not lead to any observable adverse effects during the course of study (Aziz, Hussain, Mahwi, Ahmed 2018)

AAV-NFAT5 or antagomir decreased NIK expression and increased NFAT5 and p-AKT1 levels, and METs co-labelled with citH3, the marker of METs, and F4/80 can also be suppressed (Fig