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Conclusion: The data strongly suggest that in contrast to the report that UDCA is a gut FXR antagonist, in this study, UDCA seems to act as an FXR agonist, especially in the ileum

Well absorbed S-acetyl-glutathione is one of several reversible bioconjugates of glutathione that are stable in plasma, and can be taken up by cells directly.* Stable in the stomach and gastrointestinal tract, and well absorbed* Shown to naturally replenish intracellular glutathione levels* Unlike many other forms of glutathione, acetyl-glutathione tablets are odorless, tasteless, and easy to take

S5-S8 and Tables S3-S4)

Experts on Konzo who are based at the University of Kinshasa and Institute National de Research Biomedical (INRB) helped design and execute the research activities presented in this manuscript, in collaboration with the large group of co-authors who aided in research activities related to this work