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The legitimate worry with sustained NNMT inhibition isnt tolerance in the receptor sense

It is particularly beneficial for vegans and vegetarians at risk of B12 deficiency, individuals with poor nutrient absorption, and biohackers or high performers seeking optimal energy and cognitive support

Primary Handling Editor: Isabella Samuelson, in collaboration with the Nature Metabolism team

Stacking multiple GLP-1 agonists together, such as semaglutide and tirzepatide, is generally not recommended due to overlapping mechanisms and increased side effect risk

It allowed me to focus more in my daily job, it gives me a very good boost of energy, and it simply make me feel better