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UDFF detected any steatosis (S1) with an ROC=0.76 (rule-in cutoff: UDFF22% and rule-out cutoff: UDFF 0.53 were enrolled in a screening period of 2.4 months and randomized to receive rencofilstat once daily at 75, 150, or 225 mg for 120 days

Blood 121 , 20992107 (2013)

The second top-level step is made up of alternative KOs for the glucose-6-phosphate isomerase enzyme, which converts alpha-D-Glucose 6-phosphate to beta-D-Fructose 6-phosphate

However, they also note that while findings are promising, further large-scale, controlled trials are needed to confirm the effectiveness of neurofeedback in memory improvement

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