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Adults (aged between 19 to 64) need around 1.5 microgram a day of vitamin B12

No findings imply clinical relevance, therapeutic application, physiological effects, or suitability for human or veterinary use

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Geng, L

In the clinical conditions presented in the review, increased intestinal permeability has been demonstrated, but the central question of whether the barrier dysfunction is a primary event in the pathophysiology or a consequence of the disease is still not resolved in most diseases