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J Pers Med 10(3):112 Agosti E et al (2023) Tumor microenvironment and glioblastoma cell interplay as promoters of therapeutic resistance

The complex relationship between cortisol and inflammation is shown schematically in Figure 5

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There is an urgent need for innovative, safer, and more accessible strategies to improve prevention and management

Deficiency in TNSALP leads to hypophosphatasia (HPP), an inborn error of metabolism characterized by epileptic seizures in the most severe cases, caused by abnormal metabolism of pyridoxal-5-phosphate (the predominant form of vitamin B6) and by hypomineralization of the skeleton and teeth featuring rickets and early loss of teeth in children or osteomalacia and dental problems in adults caused by accumulation of inorganic pyrophosphate (PPi) [57]