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20 There is one early blinded, placebo-controlled trial of NAC on its own in 43 patients with Alzheimers disease that found NAC, 50 mg per kg bodyweight (equivalent to 3750 mg for a person weighing 75 kg) per day for 6 months, to be superior to placebo in almost all outcome measures, although not all reached statistical significance

2008;13(2):1657 Back M, Yin L, Ingelsson E

The nutrient is then absorbed directly into the bloodstream, bypassing any potential barriers in the digestive system