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2021 Aug 13;373(6556):80812

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A hundred years ago, the author of this theory, characterized by the conversion of glucose into lactate, pointed out that this effect was the result of a mitochondrial defect, thus generating a universal metabolic alteration

Amnesia was induced via intracerebroventricular (icv) administration of scopolamine at a dose of 70 nmol in 2 l artificial cerebrospinal fluid, with control animals receiving either aCSF or distilled water