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Epub 2011 Mar 24..10.2215/CJN.01370211 [PubMed: 21441122] [CrossRef] 224

Upon IB degradation, NF-B is released and translocates into the nucleus, where it recruits p300, which in complex with cAMP response element-binding protein acetylates RelA/p65, thereby activating NF-B transcription and enhancing the expression of downstream pro-inflammatory genes (Lawrence 2009)