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SKU: 54461501419
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Mitochondria-targeted nanomedicines self-assembled from GSH-responsive paclitaxel-SS-berberine conjugates can upregulate ROS levels in cancer cells, arrest cells in the G2/M phase, induce cancer cell apoptosis, and inhibit tumor growth [237]

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In these ways, mitochondria contribute to various diseases, including tumors, cardiovascular diseases, neurodegenerative diseases, metabolic abnormalities, ocular diseases, liver diseases, and autoimmune diseases, by inducing mitochondrial dysfunction or through regulating oxidative stress, inflammation, and aging