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Overall, there are two possible pathways that mediate the interaction between immune cells and hepatocytes, one that may rely on direct cell-to-cell contacts such as cell surface receptors and ligand adhesion molecules, the other through, for example, inflammatory mediators released by these cells
Chachay VS, Macdonald GA, Martin JH, Whitehead JP, OMoore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ
Abbreviations ADI-R: Autism diagnostic interview - revised ALAD: Delta aminolevulinic acid dehydratase CARS: Childhood Autism Rating Scale CNS: Central nervous system d.f.: Degrees freedom DSM: American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders fGSH: Free reduced glutathione GCL: Glutamate cysteine ligase GCT: -glutamyl cyclotransferase GGT: -glutamyl-transferase GPx: Glutathione peroxidase GSH: Reduced glutathione GSH: GSSG: Glutathione redox ratio GSH-R: Glutathione reductase GS: Glutathione synthetase GSSG: Oxidised glutathione GST: Glutathione-S-transferases Mg 2+ : Magnesium ions Mn 2+ : Manganese ions Q: Cochran's Q (a measure of statistical heterogeneity) SMD: Standardised mean difference tGSH: Total glutathione References Wing L, Gould J: Severe impairments of social interaction and associated abnormalities in children: epidemiology and classification
This project was supported by the National Natural Science Foundation of China (823B2074 to P.C.T.), the National Key R&D Program of China (2022YFA1103704 to S.D.), Beijing Natural Science Foundation (JQ22016 to T.H.M.), the New Cornerstone Investigator Program (to S.D.), and Center for Life Sciences (to S.D.)
