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She had radicular left lower-extremity pain on movement, which worsened over the course of a year, evolving into a chronic neuropathic pain with a breakthrough component

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Sebaratnam D, 2021, '26869 Atenolol as treatment for systemic hemangiomatosis in a premature infant', Journal of the American Academy of Dermatology , 85, pp

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While MT-1 is selective for the MC1R receptor, MT-2s cyclic structure gives it structural compatibility with multiple melanocortin receptor subtypes, including MC1R, MC3R, MC4R, and MC5R