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doi: 10.3390/ijms26073059 66 ZhangYZhengTMaDShiPZhangHLiJet al

Therapeutic targeting of immunometabolism in lung cancer Recent advances in understanding the metabolic interplay between tumor cells, cancer stem-like cells, and immune cells have unveiled promising therapeutic avenues in lung cancer

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This means that ferroptosis can induce other kinds of cell death, and/or it plays a minor effect in cell death, or we use inhibitors after the reversible point and once this threshold is exceeded, ferroptosis will be irreversible Recently, we also found that ferroptosis is vital for tumor immunity such as macrophage phagocytosis (71) and T cell killing (115) but the crosstalk between ferroptosis and the glioma immunosuppressive microenvironment is not clear

[DOI] [PubMed] [Google Scholar] Bruchhausen S, Zahn S, Valk E, Knop J, Becker D