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Moreover, B vitamins such as B6 and B12 play roles in neurotransmitter production and brain function

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In bladder cancer, it induces ferroptosis mainly by inhibiting GPX4 expression (68)

495 However, DHODH inhibition in SOD2-depleted cells reduced oxidative stress, lipid peroxidation, and ferroptosis, improving survival and colony formation, suggesting that DHODH activity sustains radiation-induced ferroptosis