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Oxidative stress inhibits mTOR through intermolecular disulfide bond formation with deptor in cardiomyocytes

10.23876/j.krcp.20.163 Kidney Res Clin Pract

Intriguingly, leptin deficiency is linked to the early-onset of obesity, indicating that ratio of leptin to insulin is fundamental in the homeostatic balance of fat and glucose metabolism (Wabitsch et al., 2015)