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4e, PCA analysis indicated that principal component 1 (PC1) covered most of the variation in gene expression (58% of total variance), likely including the effect caused by Gclc deletion

Int Immunopharmacol 158:114825 Aimaiti M, Wumaier A, Aisa Y, Zhang Y, Xirepu X, Aibaidula Y, Lei X, Chen Q, Feng X, Mi N (2021) Acteoside exerts neuroprotection effects in the model of Parkinsons disease via inducing autophagy: network pharmacology and experimental study

Huang, Y., Cohen, J

Another theory relates it to the hair shaft, because samples from a group of people with KP found a hair still coiled up under the skin, causing doctors to hypothesize that those coiled hairs throw the skins keratin functioning out of whack