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Hao et al., 2024)

Some doctors advocate for giving a full year (4 rounds separated by 3-month intervals) to see the full effect

doi: 10.1053/j.gastro.2020.06.045

[12] Beyond that specific episode, GH secretagogues generally can affect glucose metabolism and insulin sensitivity: raising GH tends to oppose insulin action, and studies of oral ghrelin-mimetic secretagogues in older adults have documented measurable effects on glucose handling alongside their GH and IGF-I elevation

and preserving the shape and function of sinusoidal and hepatic cells, as well as reducing extracellular matrix (ECM) deposition (Niu et al., 2012