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It should be emphasized that during corticosteroid therapy prolonged for more than 2 weeks, there is a risk of developing adrenocortical insufficiency, which is manifested by the inhibition of ACTH secretion and adrenal atrophy

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Tragically though, pigs might fly before this happens

When taken over a long period, high potassium intake (through supplements or diet) may lower Vitamin B12 levels, especially if your diet is already lacking in B12 sources