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In cultured adipocytes, we also show that p53 signalling activation by starvation is reversible by refeeding and that it elicits not only an apoptotic but also an inflammatory gene programme

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Research suggests fixed doses provide adequate tissue exposure regardless of body size within normal ranges

They require a steady supply of antioxidants to keep their delicate filtering unitscalled nephronsfunctioning at their best

Researchers are advised to prepare small working aliquots to avoid repeated temperature cycling, which can accelerate degradation of the peptide structure