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Cell 186 , 48684884.e4812 (2023)

If SCoV2 is targeting GSH biosynthesis as well as TXNRD1 and GPx1 for proteolytic knockdown, in infected cells, the resulting decreases in these critical antioxidant molecules would contribute to increased oxidative stress, NF-B activation and pro-apoptotic signaling (32), this could contribute to increased inflammation and the cytokine storms observed in COVID-19, and be a significant basis of pathogenic effects associated with SCoV2 infection of various tissues, including the lung, gastrointestinal tract and cardiovascular system

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Portulaca Oleracea Extract, Glutathione Euglena Gracilis Polysaccharide, Hydrolyzed Collagen, Opuntia Streptacantha Stem Extract, Hyaluronic Acid, Silanetrio, Phenoxyethanol, Methyl Gluceth-20, Ethylhexylglycerin, Hydroxyethylpiperazine Ethane Sulfonic Acid

Suspected adverse reactions should be reported through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)