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Accordingly, we can hypothesize that ferroptosis may serve to regulate normal epidermal differentiation during the pathophysiology of ichthyosis

As opposed to traditional chemotherapy that works by directly destroying rapidly dividing cells, irAEs occur when increased activation of immune effector cells/mechanisms result in damage to normal cells

importante distinguir as variantes do CJC

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes