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Dermal thickness, defined as the distance from the epidermaldermal junction to the dermaladipose junction or to the loose connective tissue subjacent to the panniculus carnosus, respectively, were determined at five randomly selected sites per h.p.f., as previously described 65

Moreover, the buildup of fats in muscle cells is associated with lower insulin sensitivity in adults who do not exercise regularly, suggestive of reduced muscle quality

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Thiemann S, Smit N, Roy U, Lesker TR, Glvez EJC, Helmecke J, et al